منابع مشابه
Addiction , Dopamine , and the Review
The central feature of drug addiction is compulsive drug of a motor activity, such as sniffing or biting (Randrup use—loss of control over apparently voluntary acts of and Munkvad, 1967). If cocaine or amphetamine is used drug seeking and drug taking (Goldstein, 1994). Addicrepeatedly, some acute drug effects may diminish (“toltion is a chronic disorder, since even after treatment erance”), whi...
متن کاملDopamine in Addiction and Obesity
Each month the editor of Newsline selects articles on diagnostic, therapeutic, research, and practice issues from a range of international publications. Most selections come from outside the standard canon of nuclear medicine and radiology journals. These briefs are offered as a monthly window on the broad arena of medical and scientific endeavor in which nuclear medicine now plays an essential...
متن کاملAddiction: beyond dopamine reward circuitry.
Dopamine (DA) is considered crucial for the rewarding effects of drugs of abuse, but its role in addiction is much less clear. This review focuses on studies that used PET to characterize the brain DA system in addicted subjects. These studies have corroborated in humans the relevance of drug-induced fast DA increases in striatum [including nucleus accumbens (NAc)] in their rewarding effects bu...
متن کاملDopamine signaling in food addiction: role of dopamine D2 receptors
Dopamine (DA) regulates emotional and motivational behavior through the mesolimbic dopaminergic pathway. Changes in DA signaling in mesolimbic neurotransmission are widely believed to modify reward-related behaviors and are therefore closely associated with drug addiction. Recent evidence now suggests that as with drug addiction, obesity with compulsive eating behaviors involves reward circuitr...
متن کاملBrain dopamine response in human opioid addiction.
BACKGROUND Drugs of dependence cause dopamine release in the rat striatum. Human neuroimaging studies have shown an increase in dopamine in the equivalent region in response to stimulants and other drugs. AIMS We tested whether opioids provoke dopamine release and its relationship to the subjective experience. METHOD In two combined studies 14 heroin addicts on methadone maintenance treatme...
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ژورنال
عنوان ژورنال: Journal of Experimental and Basic Medical Sciences
سال: 2020
ISSN: 2717-9478
DOI: 10.5606/jebms.2020.75607